ESTABLISHMENT OF BIOCONTROL AGENTS AND THEIR IMPACT ON RHIZOSPHERE MICROBIOME AND INDUCED GRAPEVINE DEFENSES ARE HIGHLY SOIL-DEPENDENT

Establishment of Biocontrol Agents and Their Impact on Rhizosphere Microbiome and Induced Grapevine Defenses Are Highly Soil-Dependent

With a reduction in available chemical treatments, there is an increased interest in biological control of grapevine trunk diseases.Few studies have investigated the impact of introducing beneficial Swim Tops microorganisms in the rhizosphere on the existing indigenous soil microbiome.In this study, we explored the effect of two biocontrol agents (

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Soil fungal biodiversity and pathogen identification of rotten disease in Aconitum carmichaelii (Fuzi) roots.

Aconitum carmichaelii, commonly known as Fuzi, is a typical traditional Chinese medicine (TCM) herb that has been grown for more than one thousand years in China.Although root rot disease has been seriously threatening this crop in recent years, few studies have investigated root rot disease in Fuzi, and no pathogens have been identified.In this st

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The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy

Summary: CHK1 inhibitors exhibit dose-limiting toxicity despite potent tumor cytotoxicity in clinical trials.Here, we reveal that low-dose prexasertib induces mtDNA damage by impairing repair machinery, triggering cytosolic mtDNA release via VDAC1 to activate STING-mediated innate immunity.Mechanistically, prexasertib blocks CHK1 phosphorylation an

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Policy and behavioral response to shock events: An agent-based model of the effectiveness and equity of policy design features.

In the aftermath of shock events, policy responses tend to be crafted under significant time constraints and high levels of uncertainty.The extent to which Oven Door Lock individuals comply with different policy designs can further influence how effective the policy responses are and how equitably their impacts are distributed in the population.Too

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